Health Minister Brad Hazzard said works are expected to commence later this year following a competitive tender process.

"The NSW Government is committed to investing in rural and regional health infrastructure to support better health outcomes for local communities," Mr Hazzard said.

"Our paramedics need the best possible workplace to provide emergency medical care, and the infrastructure improvements will make a real difference to their working environment."

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The range of enhancements at the Tenterfield Ambulance station include new roller shutters, new amenities and internal upgrades including a refurbishment of walls, ceilings and floors.

MP Janelle Saffin welcomed the announcement of a major refurbishment for the station.

"This is great news for Tenterfield Shire residents who rely on their ambulance station for transport and care during medical and day-to-day emergencies, particularly given Tenterfield's proximity to the Queensland border," she said.

"I have requested a full briefing on the station upgrade from Minister Hazzard's office, to get appraised of the detail, but I welcome his announcement."

Minister Hazzard confirmed the news during Question Time in State Parliament on Wednesday.

"And the Member for Lismore (Janelle Saffin) should be happy there is a refurbishment of a station at Tenterfield, which is a particularly significant area, obviously, close to the border," Mr Hazzard told Parliament.

The NSW Government is investing $232 million to deliver the RAIR program under Stages 1 and 2.

The refurbishment is on top of the $312 million Lismore Hospital Redevelopment. Its final stage is expected to be completed late 2021 and include new and expanded inpatient wards, a new intensive care unit /high dependency unit, new education, training and research facilities and new administration facilities.