The New England highway will be closed intermittently overnight as work crews make emergency repairs at the Bolivia Hill works.
Transport for NSW warns that during road closures traffic will be stopped in both directions causing delays of up to 20 minutes.
The repairs will be carried out overnight between 7pm and 5am.
TfNSW says pavement repair work is necessary to ensure the ongoing safety of motorists and workers.
Outside full closure, motorists should expect the normal delay of up to 10 minutes.
Traffic control and a reduced speed limit of 40 km/h will be in place for the safety of workers and motorists. Motorists are advised to drive to the conditions and follow the direction of traffic signals and traffic control.